England have added scrum-halves Ben Spencer and Harry Randall to their Nations Championship squad after injuries ruled out Alex Mitchell and Archie McParland.
Mitchell suffered a hamstring injury in Northampton's win over Gloucester, while uncapped McParland picked up a calf injury in training. Mitchell will have a scan on Monday; McParland could still be in contention for later matches.
Jack van Poortvliet is set to remain first-choice scrum-half. At fly-half, Fin Smith is struggling with a calf problem, with Marcus Smith and George Ford competing to deputise.
Saracens hooker Theo Dan secures the third hooker spot, replacing injured Kepu Tuipulotu. Gloucester centre Seb Atkinson and Exeter wing Immanuel Feyi-Waboso return from injury.
Midfield selection includes Will Joseph and Joe Marchant, while Ollie Lawrence, Max Ojomoh, and Noah Caluori are omitted. England face Australia on 8 November at Twickenham, followed by Japan and New Zealand, with a play-off final against a southern hemisphere opponent.
