All 16 Week 8 NFL games will be played domestically after a week of international matchups. The schedule features several potential playoff rematches, including Ravens at Bills (Buffalo favored by 3), Vikings at Lions (Detroit -3.5), Chiefs at Broncos (Kansas City -1.5) and Bears at Seahawks (Seattle -3). Other notable lines include Bengals -13.5 vs Titans, Jaguars -10.5 vs Colts and Rams -6.5 vs Chargers.
An advanced computer model that simulates every game 10,000 times has produced betting picks for the entire slate. Since its inception the model has returned more than $5,000 for $100 players on top-rated picks and entered Week 8 on a 58-51 run dating back to 2024.
Among the model's strongest selections: Pittsburgh (-3.5, total 39) covers at home against Cleveland. The Steelers have won 22 consecutive home games versus the Browns since 2004, are 3-0 against the spread at home this season, and have scored 30-plus points in back-to-back home games. Cleveland's offense ranks 28th in scoring and is 2-2 ATS on the road.
Another highlighted pick: Los Angeles Rams (-6.5, total 45.5) cover against the Chargers. Los Angeles has lost nine straight games dating to last season, with quarterback Justin Herbert throwing 12 turnovers against six touchdowns over that span. The Chargers are winless against the spread during the streak, while the Rams are 6-2 ATS in non-conference games since 2025, the second-best mark in the league. The model projects a touchdown-plus victory with the over hitting 55% of simulations.
The model also identifies six teams projected to win by double digits, offering potential value on alternate lines. Full game-by-game picks and updated odds are available from the simulation service.
