As the NFL heads into Week 9, several matchups present notable betting trends and expert predictions. A standout trend involves the Seattle Seahawks hosting the Arizona Cardinals on Sunday at 4:25 p.m. ET. Four of the last five meetings in Seattle have been decided by exactly 10 points, and the Seahawks have won 10 consecutive games against the Cardinals regardless of location. Seattle enters as an 8.5-point favorite, with the line dropping from an opening 12.5 points after Drew Lock was named starter in place of the injured Sam Darnold, while Gardner Minshew will start for Arizona.
Other Notable Spreads
Other games with a spread of at least a touchdown include the Detroit Lions versus the Miami Dolphins (+6.5), the San Francisco 49ers versus the Las Vegas Raiders (+9.5), and the Kansas City Chiefs versus the New York Jets (+9.5).
Expert Analysis
SportsLine expert Eric Cohen, who finished the 2025-26 season with a 188-96-1 straight-up record (66%) and is 70-50-1 (58%) on 2026 picks, has analyzed the full Week 9 slate. Cohen recommends backing the 49ers (-9.5, 51.5) to defeat the Raiders, with the Over also hitting. San Francisco is 8-1 straight-up following its last nine bye weeks, while the Raiders are 1-5 over their last six games with a rest disadvantage. Both teams rank in the top six in scoring offense, but Las Vegas ranks 31st in scoring defense compared to San Francisco's sixth-ranked unit. Cohen notes that six straight Raiders games have produced 56 or more points and hit the Over, a trend he expects to continue. He projects a 34-24 final score in favor of the 49ers.
Additional Insights
Cohen has also identified five games projected to be decided by 13 or more points, which could offer significant value on alternate lines. Detailed score predictions for all 15 Week 9 games are available through his analysis.
